Start Semaglutide with a 0.25 mg subcutaneous injection (injection under the skin) once weekly for 4 weeks. The 0.25 mg dosage is intended for treatment initiation and is not effective for glycemic control.
After 4 weeks on the 0.25 mg dosage, increase the dosage to 0.5 mg once weekly.
If additional glycemic control is needed after at least 4 weeks on the 0.5 mg dosage, the dosage may be increased to 1 mg once weekly.
If additional glycemic control is needed after at least 4 weeks on the 1 mg dosage, the dosage may be increased to 2 mg once weekly. The maximum recommended dosage is 2 mg once weekly.
Administer Semaglutide once weekly, on the same day each week, at any time of the day, with or without meals.
The day of weekly administration can be changed if necessary as long as the time between two doses is at least 2 days (>48 hours).
If a dose is missed, administer Semaglutide as soon as possible within 5 days after the missed dose. If more than 5 days have passed, skip the missed dose and administer the next dose on the regularly scheduled day. In each case, patients can then resume their regular once weekly dosing schedule.
Caution:
After using a sterile syringe to extract sterile water, insert the syringe into the Semaglutide vial and mix the powder and sterile water thoroughly before subcutaneously injecting. (Be sure to push out sterile water with the syringe needle close to the vial wall)
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